Benefits
- Helps to promote normal synthesis and regeneration of cartilage
- Helps to maintain joint comfort
- Helps to support joint fluidity and flexibility
- Supports overall joint health
This product is not intended to diagnose, treat, cure or prevent any disease.

Product Classifications
Gluten-Free - The finished product contains no detectable gluten*
No Detectable GMO - The finished product contains no detectable genetically modified organisms
Isotonic-Capable Supplements - Easy-to-take isotonic supplements / health food that allow for better nutrient absorption by the body
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Potency, Purity and Identity
*USA FDA classifies gluten-free as a finished product containing less than 20PPM gluten
Details
As the body ages, many people experience joint discomfort. One option is to take a joint supplement to help promote overall bone and joint health. Prime Joint Powder Drink by Isotonix directly provides hyaluronic acid. Hyaluronic acid plays an important role in tissue hydration and lubrication. It also contains glucosamine, which is naturally produced by the body and acts as a key component of cartilage. An aminomonosaccharide (a combination of the amino acid — glutamine and a sugar — glucose), glucosamine is concentrated in joint cartilage, where it supports healthy joint function. Prime Joint Support Formula also contains the powerful antioxidant Pycnogenol®†.
Prime Joint Power Drink by Isotonix is a unique product that delivers glucosamine,
Pycnogenol and hyaluronic acid in an isotonic form. Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do to obtain maximum absorption of the nutrients. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and rapidly absorb into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients efficient while delivering maximum results.
†Pycnogenol® is registered trademark of Horphag Research, Ltd. Use of this product may be protected by one or more U.S patents and other international patents.

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Isotonix Delivery System

Ingredients
Glucosamine
Glucosamine is a molecule that is naturally synthesized in the body from glucose and the amino acid glutamine. Glucosamine is an important constituent of glycosaminoglycans in cartilage matrix and synovial fluid. As our bodies age, we are less able to produce glucosamine, resulting in cartilage that is less flexible and weak. Although the mechanism is currently unclear, studies have shown that glucosamine supplementation can support normal, healthy cartilage cell production to support overall joint health.
Pine Bark Extract (Pycnogenol®)
Pycnogenol is a water-soluble flavonoid complex with powerful benefits. Pycnogenol, similar to the proanthocyanins found in grape seeds, is extracted from the bark of the French maritime pine tree. Pycnogenol has been shown help maintain the body’s natural defenses and supporting good health. In addition, studies have shown Pycnogenol has the ability to support the cross-linking of collagen fibers and other connective tissue.
Hyaluronic Acid
Hyaluronic acid plays an important role in tissue hydration and lubrication. Although it is produced naturally by the body, the level of hyaluronic acid diminishes with age, contributing to joint discomfort. It is a key component of cartilage and is important for joint health. Hyaluronic acid has been shown to help maintain strong, healthy cartilage and enhance synovial fluid production.
FAQ
Who should take Prime Joint Powder Drink by Isotonix?
This product is for ADULT USE ONLY. This product would be good for any adult that wishes to support and maintain healthy joints.
What other products should I take with Prime Joint Powder Drink by Isotonix to support my joint health?
Heart Health™ Essential Fish Oil is a great pair with Prime Joint Powder Drink by Isotonix, as omega III fatty acids have been shown to support healthy joint lubrication.
How should I take Prime Joint Powder Drink by Isotonix?
Pour two (2) level, white bottle capfuls of powder into a cup. Add 120 ml of water and stir. As a health food, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken on an empty stomach. This product is isotonic only if the specified amounts of powder and water are used.
How much Pycnogenol® is in Prime Joint Powder Drink by Isotonix?
There are 25 milligrams of Pycnogenol in each daily serving.
Is Prime Joint Powder Drink by Isotonix safe?
The product is safe and free of harmful agents. This product is made in the United States in FDA-inspected facilities using Good Manufacturing Practices. Customers can have confidence in the quality and safety of this product.
Science
- Belcaro, G., et al. Variations in C-reactive protein, plasma free radicals and fibrinogen values in patients with osteoarthritis treated with Pycnogenol®. Redox Report. 13(6): 271-276, 2008.
- Blewis, M., et al. A model of synovial fluid lubricant composition in normal and injured joints. European Cells and Materials. 13: 26-39, 2007.
- Braham, R., et al. The effect of glucosamine supplementation on people experiencing regular knee pain. British Journal of Sports Medicine. 37(1): 45-49, 2003.
- Canali, R., et al. The anti-inflammatory pharmacology of Pycnogenol® in humans involves COX-2 and 5-LOX mRNA expression in leukocytes. International Immunopharmacology. 9(10): 1145-1149, 2009.
- Chang, X., et al. Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis. Arthritis Research and Therapy. 7(2): R268-R273, 2005.
- Chou, M., et al. Effects of chondroitin and glucosamine sulfate in a dietary bar formulation on inflammation, interleukin-1beta, matrix metalloprotease-9, and cartilage damage in arthritis. Experimental Biology and Medicine. 230(4): 255-262, 2005.
- Cisár, P., et al. Effect of pine bark extract (Pycnogenol®) on symptoms of knee osteoarthritis. Phytotherapy Research. 22: 1087-1092, 2008.
- Elliott, A., et al. Serum hyaluronan levels and radiographic knee and hip osteoarthritis in African Americans and Caucasians in the Johnston County Osteoarthritis Project. Arthritis and Rheumatism. 52(1): 105-111, 2005.
- Farid, R., et al. Pycnogenol® supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritis. Nutrition Research. 27: 692-697, 2007.
- Gaby, A. Natural treatments for osteoarthritis. Alternative Medicine Review. 4(5): 330-341, 1999.
- Gouze, J., et al. Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta. Arthritis Research and Therapy. 8(6): R173
- Grimm, T., et al. Inhibition of NF-kappaB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol®). Journal of Inflammation. 3: 1-15, 2006.
- Hua, J., et al. Inhibitory actions of glucosamine, a therapeutic agent for osteoarthritis, on the functions of neutrophils. Journal of Leukocyte Biology. 71(4): 632-640, 2002.
- James, C. and Uhl, T. A review of articular cartilage pathology and the use of glucosamine sulfate. Journal of Athletic Training. 36(4): 413-419, 2001.
- Julovi, S., et al. Inhibition of interleukin-1beta-stimulated production of matrix metalloproteinases by hyaluronan via CD44 in human articular cartilage. Arthritis and Rheumatism. 50(2): 516-525, 2004.
- Laurent, T., et al. Functions of hyaluronan. Annals of the Rheumatic Disease. 54(5): 429-432, 1995.
- Kelly, G. The role of glucosamine sulfate and chondroitin sulfates in the treatment of degenerative joint disease. Alternative Medicine Review. 3(1): 27-39, 1998.
- McDonald, J. and Levick, J. Hyaluronan reduces fluid escape rate from rabbit knee joints disparately from its effect on fluidity. Experimental Physiology. 79(1): 103-106, 1994.
- Nakatani, S., et al. Glucosamine regulates differentiation of a chondrogenic cell line, ATDC5. Biological and Pharmaceutical Bulletin. 30(3): 433-438, 2007.
- Ohno, S., et al. Hyaluronan oligosaccharides induce matrix metalloproteinase 13 via transcriptional activation of NFkappaB and p38 MAP kinase in articular chondrocytes. Journal of Biological Chemistry. 281(26): 17952-17960, 2006.
- Poustie, M., et al. N-butyryl glucosamine increases matrix gene expression by chondrocytes. Journal of Pharmacology and Experimental Therapeutics. 311(2): 610-616, 2004.
- Reginster, J., et al. Current concepts in the therapeutic management of osteoarthritis with glucosamine. Bulletin (Hospital for Joint Disease). 63(1-2): 31-36, 2005.
- Reginster, J., et al. Long-term effects of glucosamine sulphate on osteoarthritis progression: a randomized, placebo-controlled clinical trial. Lancet. 357(9252): 251-256, 2001.
- Richy, F., et al. Structural and symptomatic efficacy of glucosamine and chondroitin in knee osteoarthritis: a comprehensive meta-analysis. Archives of Internal Medicine. 163(13): 1514-1522, 2003.
- Santangelo, K., et al. Effects of hyaluronan treatment on lipopolysaccharide-challenged fibroblast-like synovial cells. Arthritis Research and Therapy. 9(1): R1, 2007.
- Sasaki, A., et al. Hyaluronate inhibits the interleukin-1beta-induced expression of matrix metalloproteinase (MMP)-1 and MMP-3 in human synovial cells. The Tohoku Journal of Experimental Medicine. 204(2): 99-107, 2004.
- Schäfer, A., et al. Inhibition of COX-1 and COX-2 activity by plasma of human volunteers after ingestion of French maritime pine bark extract (Pycnogenol®). Biomedicine and Pharmacotherapy. 60: 5-9, 2006
Reviews
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5.0 out of 5 star rating.
(5 reviews)
would recommend this product.
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我個仔每日工作都要行樓梯, 膝蓋經常出現痛楚, 自從我每日俾健絡關節和菠蘿酵素給他飲後, 情況明顯大大改善.
Response from Customer Service on 26/5/2021
致 親愛的顧客,
感謝您抽出寶貴時間對Prime™ Isotonix®健絡關節沖飲發表意見。 我們很高興您對產品感到滿意。
再次感謝閣下對美安的支持!
超連鎖店主服務部 謹啟
Prime joint 產品
by Anonymous
on 18/9/2019
我朋友食過幾種骨骼補健產品,最後都覺得Prime joint 最好,一買就買咗4瓶。
健絡關節
by Anonymous
on 1/5/2019
👍👍👍
腳痛改善了
by Anonymous
on 21/2/2019
媽媽飲了一個月,明顯膝蓋關節改善了,行路靈活很多
幫助關節
by Li
Shop Consultant
on 8/10/2018
用了後感覺關節感覺更好。在外工作一天之後,關節沒有那麼僵硬。超讚的產品!!
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