Benefits
- Helps maintain healthy circulation
- Helps maintain brain health
- Promotes healthy nitric oxide levels
- Provides antioxidant defense
- Powerful free-radical scavenger
This product is not intended to diagnose, treat, cure or prevent any disease.
Product Classifications
Gluten-Free - The finished product contains no detectable gluten*
Vegan - The product is made without ingredients produced by or derived from animals
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Potency, Purity and Identity
*USA FDA classifies gluten-free as a finished product containing less than 20PPM gluten
Details
The formula for OPC-3 Chews includes some of the most powerful bioflavonoids currently known to research scientists. These bioflavonoids are scientifically termed oligomeric proanthocyanidins, commonly abbreviated OPCs. Studies have shown OPCs to be up to 20 times more powerful than vitamin C and 50 times more powerful than vitamin E in neutralizing free radicals. The best-researched OPCs are from grape seed, red wine, grape skin, bilberries, citrus fruit and Pycnogenol®†. The combination of these powerful OPCs is unique to OPC-3.
OPC-3 Chews provide you with all the benefits of Isotonix OPC-3 Powder Drink in a delicious and convenient soft chew alternative, using natural flavors, colors and sweeteners. OPC-3 Chews are designed to provide antioxidant defense, as well as a variety of other health benefits.
†Pycnogenol® is registered trademark of Horphag Research, Ltd. Use of this product may be protected by one or more U.S patents and other international patents.

Ingredients
Pycnogenol®
Pycnogenol® is a plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. This unspoiled, natural environment is the unique source of this pine bark. Pycnogenol® is one of the most researched ingredients in the natural product marketplace. Published findings have demonstrated Pycnogenol®'s wide array of beneficial effects on the body, specifically in the realm of antioxidant health. Pine bark extract is a combination of proanthocyanidins, bioflavonoids, and organic acids.
Grape Seed Extract
Grape seed extract is typically extracted from the seeds of red grapes (instead of white), which have a high content of compounds known as oligomeric proanthocyanidins (OPCs). Grape seed extract contains polyphenols, compounds with antioxidant activity. Individuals benefit from grape seed extract because it provides antioxidant defense and may help maintain healthy circulation.
Bilberry Extract
Bilberry extract is derived from a berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry contain flavonoid pigments known as anthocyanins, which act as antioxidants. Studies support that bilberry extract may help maintain healthy circulation.
Citrus Bioflavonoids Extract
Bioflavonoids are antioxidants found in certain plants that act as light filters, which protect the plant's DNA and other important macromolecules by absorbing ultraviolet radiation. They may help maintain healthy circulation.
Red Wine Extract
Red Wine extract is derived from grapes. High in antioxidant properties, red wine extract acts as a free radical scavenger. It may also help maintain healthy circulation.
FAQ
What are OPCs?
The formula for OPC-3 Fruit Flavored Chews For Adults includes bioflavonoids – biologically-active members of plant-derived compounds. These bioflavonoids are also known as oligomeric proanthocyanidins which are commonly abbreviated OPCs. Some of the most well researched OPCs include grape seed, red wine, grape skin, bilberries, citrus fruit, and pine bark extract (Pycnogenol).
Are there any allergens in OPC-3 Chews?
OPC-3 Chews is a vegetarian product and contains no wheat, soy, yeast, gluten, artificial flavor, starch, salt, preservatives or milk.
What is the serving size for OPC-3 Chews?
Consume one (1) chew daily or as directed by your healthcare provider.
What is the best storage condition for OPC-3 Chews?
Keep the chews in the sealed pouch at all times. Seal the pouch after each opening. Store in a cool, dry place, such as refrigerator or dry box.
Is OPC-3 Chews safe?
The product is safe and free of harmful chemicals, preservatives and alcohol. The product is made in the United States in FDA-inspected facilities using Good Manufacturing Practices. Customers can have confidence in the quality and safety of this product.
Science
- Burton G et al. Vitamin E: Antioxidant activity, biokinetics, and bioavailability. Annual Review Nutrition. 10:357-382, 1992.
- Devaraj S et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 37:931-4, 2002.
- Diliberto E et al. Multicompartmental secretion of ascorbate and its dual role in dopamine b-hydroxylation. American Journal of Clinical Nutrition. 54(6 Supplement):1163S-72S, 1991.
- Fine A. Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Alternative Medicine Review 5:144-51, 2000. Review.
- Fitzpatrick, D., et al. Endothelium-dependent vascular effects of Pycnogenol. Journal of Cardiovascular Pharmacology 32: 509-515, 1998.
- Freedman, J., et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation 103:2792-8, 2001.
- Frei B et al. Ascorbate is an outstanding antioxidant in human blood plasma. Proceedings of the National Academy of Sciences USA. 86(16):6377-6381, 1989.
- Gulati, O. Pycnogenol® in venous disorders: a review. European Bulletin of Drug Research 7: 1-13, 1999.
- Guo Q et al. Electron spin resonance study of free radicals formed from a procyanidin-rich pine ( Pinus maritima ) bark extract, Pycnogenol®. Free Radical Biology Medicine. 7(11-12): 1308-1312, 1999.
- Henning S et al. Glutathione blood levels and other oxidant defense indexes in men fed diets low in vitamin C. Journal of Nutrition. 121:169-175, 1991.
- Johnston C et al. Vitamin C elevates red blood cell glutathione in healthy adults. American Journal of Clinical Nutrition. 58(1):103-105, 1993.
- Kim J et al. Effect of select antioxidants on malondialdehyde modification of proteins. Nutrition. 16: 1079-1081, 2000.
- Kirsch M et al. Ascorbate is a potent antioxidant against peroxynitrite-induced oxidation reactions. Evidence that ascorbate acts by re-reducing substrate radicals produced by peroxynitrite. Journal of Biological Chemistry. 275(22):16702-16708, 2000.
- Kuo C et al. Ascorbic acid, an endogenous factor required for acetylcholine release from the synaptic vesicles. Japan Journal of Pharmacology. 30(4):481-492, 1980.
- Lenton K et al. Vitamin C augments lymphocyte glutathione in subjects with ascorbate deficiency. American Journal of Clinical Nutrition. 77(1):189-195, 2003.
- Meydani M. Protective role of dietary vitamin E on oxidative stress in ageing. Age. 15:89-93, 1992.
- Monograph. Vaccinium myrtillus (bilberry). Alternative Medicine Review 6:500-4, 2001.
- Nelson A et al. Pycnogenol® inhibits macrophage oxidative burst, lipoprotein oxidation and hydroxyl radical-induced DNA damage. Drug Development and Industrial Pharmacy. 24 (2): 139-144, 1998.
- Nishioka K et al. Pycnogenol, French maritime pine bark extract, augments endothelium-dependent vasodilation in humans. Hypertension Research. 30(9):775-80, 2007.
- Numakawa Y et al. Vitamin E protected cultured cortical neurons from oxidative stress-induced cell death through the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase. Journal of Neurochemistry. 97(4):1191-1202, 2006.
- Nuttall S et al. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther 23: 385-89, 1998.
- Packer L et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radicals in Biology and Medicine. 27:704-24, 1999. Review.
- Paleologos M et al. Cohort Study of Vitamin C Intake and Cognitive Impairment. American Journal of Epidemiology. 148(1):45-50, 1998.
- Rohdewald P. A review of the French maritime pine bark extract (Pycnogenol®), an herbal medication with a diverse clinical pharmacology. International Journal of Clinical and Pharmacology Therapeutics. 40:158-68, 2002. Review.
- Shi, J., et al. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6:291-9, 2003. Review.
- Wallerath, T., et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106:1652-8, 2002.
- Wei Z et al. Pycnogenol enhances endothelial cell antioxidant defense. Redox Report 3: 219-24, 1997.
Reviews
Customer Rating
4.8 out of 5 star rating.
(5 reviews)
would recommend this product.
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非常好,老人家唔肯飲水嘅,介紹此產品好好食
Response from Customer Service on 14/11/2023
致 親愛的顧客,感謝您抽出寶貴時間對OPC-3®軟糖 - 單袋裝發表意見。我們很高興您對產品感到滿意。再次感謝閣下對美安的支持!
超連鎖店主服務部 謹啟
好
by Anonymous
on 25/1/2023
好
Response from Customer Service on 26/1/2023
致 親愛的顧客,感謝您抽出寶貴時間對OPC-3®軟糖發表意見。我們很高興您對產品感到滿意。再次感謝閣下對美安的支持!
超連鎖店主服務部 謹啟
OPC3 軟糖
by JoannaS
on 16/4/2022
比沖水的方便,亦很可口,全家大人小朋友一起服用。
Response from Customer Service on 19/4/2022
親愛的顧客,感謝您抽出寶貴時間對OPC-3®軟糖 發表意見。我們很高興您對產品感到滿意。再次感謝閣下對美安的支持!
超連鎖店主服務部 謹啟
OPC-3 Chewables
by SMITH
Shop Consultant
on 6/6/2019
Wonderful product. No need for water and can enjoy anywhere. Great pick-me-up! Even the kids will love it and it is good for them!
方便又保健
by Anonymous
on 8/9/2016
好味
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