Shine Bright with Essential Support
70%
Over 70% of Hong Kong people are vitamin D deficient. Vitamin D plays an essential role in bone, heart, and immune health, and works with vitamin K to support absorption of calcium and healthy arteries.
600IU
of vitamin D in each serving

Vitamin D3 (Cholecalciferol)
Vitamin D promotes the efficient intestinal absorption of calcium, primarily in the duodenum and jejunum by supporting the synthesis of calcium-binding proteins to promote normal calcium absorption and retention. Vitamin D also promotes the normal formation of bone and normal bone growth and bone remodeling by osteoblasts and osteoclasts.

Product Classification

Gluten-Free

Vegetarian

Isotonic

Good Manufacturing Practices

No Detectable GMO
How to Take for Maximum Absorption

Pour 1 small capful (3.3 g) of Isotonix powder into a cup.

Add 60 ml of water for each capful and mix.

Enjoy one serving a day. For maximum absorption, take Isotonix powder drink with a meal.
Key Ingredients & Benefits

Vitamin D3 (Cholecalciferol)
promots strong bones, supports the body’s normal modulation of neuromuscular function and immune function

Vitamin K2 (Menaquinone-7)
supports proper calcium utilization, whereby adequate metabolism of calcium supports arterial and bone health
Benefits Beyond Your Bones
Isotonix Vitamin D with K2 Powder Drink contains vitamin D3, the metabolically active form of vitamin D, along with vitamin K2, a form of vitamin K which supports vascular health and calcium utilization. Vitamin D plays an important role in bone health, heart health and immune support while working with vitamin K to support normal absorption of calcium, and promote healthy arteries.
Isotonix Liquid vs. Standard Tablet & Capsule

0.05 minutes
Isotonic Liquid:
- Rapidly aborsbed by the body
- Enhanced nutriton absorption through osmotic pressure
- Free from artificial colors or flavors
- No binders or fillers to impede nutrion release
- Maximum results

0:40 minutes
Standard Tablet & Capsule:
- Difficult to swallow
- Slowly absorbed by the body
- Reduced absorption of vitamins & minerals
- Binders and fillers impede nutrient release
- Often contains artificial colors or flavors
Frequently Asked Questions
Why is vitamin K included in Isotonix Vitamin D with K2 Powder Drink?
Vitamin K is included in this product because of its unique partnership with vitamin D. Vitamins K and D work together to promote healthy calcium absorption and utilization. Vitamin K supports the delivery of calcium to the bones and helps maintain arterial health.
Is Isotonix Vitamin D with K2 Powder Drink safe for people on anti-coagulant medications?
Some studies have concluded that vitamin K2 does not interfere with anticoagulant medications. However, most products containing vitamin K (including K1 and/or K2) warn users taking anticoagulants not to take the product. So, if you are currently taking warfarin or another anticoagulant medication, you should consult your healthcare provider before taking any product containing vitamin K1 or K2.
How do I take Isotonix Vitamin D with K2 Powder Drink?
Pour 1 level, white bottle capful of powder into the overcap. Add water to the line on the overcap (60 ml) and stir. As a dietary supplement, take once daily or as directed by your healthcare provider. Maximum absorption occurs when taken with a meal.
Is it safe to take more than one serving of this product daily?
One serving daily of Isotonix Vitamin D with K2 Powder Drink is recommended. Check with your healthcare provider before taking additional daily servings of this product.
What are dietary sources of vitamin D?
Foods rich in vitamin D include cod liver oil, salmon, mackerel and tuna.
Does this product have “No Detectable GMOs”?
This product is tested with no GMO detected. This product’s raw material may contain genetically modified materials/ingredients, but the finished product does not contain any transgenic DNA fragment or transgenic proteins.
Is Isotonix Vitamin D with K2 Powder Drink safe?
The product is safe and free of harmful agents. The product is made in the United States in FDA-inspected facilities using Good Manufacturing Practices.
Research Scope
Scientific Reference List
- Adorini L. Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases. International Immunopharmacology. 2(7):1017-1028, 2002.
- American Journal of Epidemiology. 168(8):915-24, 2008. · Deluca H et al. Vitamin D: its role and uses in immunology. FASEB Journal. 15(14):2579-2585, 2001.
- Argiles A et al. Blood pressure is correlated with vitamin D(3) serum levels in dialysis patients. Blood Purification. 20(4):370-375, 2002.
- Bekner K. The vitamin K-dependent carboxylase. Journal of Nutrition. 130(8):1877-1880, 2000.
- Binkley N et al. Vitamin K nutrition and osteoporosis. Journal of Nutrition. 125(7):1812-1821, 1995.
- Bischoff-Ferrari Het al. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 293(18):2257-2264, 2005.
- Blackmore K et al. Vitamin D from dietary intake and sunlight exposure and the risk of hormone-receptor-defined breast cancer.
- Cantorna M et al. Mounting evidence for vitamin D as an environmental factor affecting autoimmune disease prevalence. Experimental Biology and Medicine ( Maywood ). 229(11):1136-1142, 2004.
- Cantorna M. Vitamin D and autoimmunity: is vitamin D status an environmental factor affecting autoimmune disease prevalence? Society for Experimental Biology and Medicine. 223:230-233, 2000.
- Chapuy M et al. Vitamin D3 and calcium to prevent hip fractures in the elderly women. New England Journal of Medicine. 327(23):1637-1642, 1992.
- Chlebowski R et al. Vitamin K in the treatment of cancer. Cancer Treatment Review. 12:49-63, 1985.
- Garber, A. K., et al. Comparison of phylloquinone bioavailability from food sources or a supplement in human subjects. Journal of Nutrition. 129(6):1201-1203, 1999.
- Garland C et al. The role of vitamin D in cancer prevention. American Journal of Public Health. 96(2):252-61, 2006.
- Giovannucci E et al. Prospective study of predictors of vitamin D status and cancer incidence and mortality in men. Journal of the National Cancer Institute. 98(7):451-459, 2006.
- Gorham E et al. Vitamin D and prevention of colorectal cancer. Journal Steroid Biochemistry and Molecular Biology. 97(1-2):179-94, 2005.
- Grant W and Holick M. Benefits and requirements of vitamin D for optimal health. Alternative Medicine Review. 10:94-111, 2005.
- Grant W et al. Reviews: A critical review of studies on vitamin D in relation to colorectal cancer. Nutrition and Cancer. 48(2):115-123, 2004.
- Guirguis-Blake J et al. Oral vitamin D3 decreases fracture risk in the elderly. Journal of Family Practice. 52(6):431-435, 2003.
- Gundberg C et al. Vitamin K status and bone health: an analysis of methods for determination under carboxylated osteocalcin. Journal of Clinical Endocrinology and Metabolism. 83(9):3258-3266, 1998.
- Habu D et al. Role of vitamin K2 in the development of hepatocellular carcinoma in women with viral cirrhosis of the liver. JAMA. 292(3):358-361, 2004.
- Harris D et al. Vitamin D and colon carcinogenesis. Journal of Nutrition. 134(12):3463S-3471S, 2004.
- Hayes C et al. The immunological functions of the vitamin D endocrine system. Cellular and Molecular Biology. 49(2):277-300, 2003.
- Hidaka T et al. Treatment for patients with postmenopausal osteoporosis who have been placed on HRT and show a decrease in bone mineral density: effects of concomitant administration of vitamin K(2). Journal of Bone and Mineral Metabolism. 20(4):235-239, 2002.
- Hiruma Y et al. Vitamin K(2) and geranylgeraniol, its side chain component, inhibited osteoclast formation in a different manner. Biochemical Biophysical Research Communications. 314(1):24-30, 2004.
- Hitomi M et al. Antitumor effects of vitamins K1, K2 and K3 on hepatocellular carcinoma in vitro and in vivo. International Journal of Oncology. 26(3):713-720, 2005.
- Holick, M. Vitamin D: Its role in cancer prevention and treatment. Progress in Biophysics and Molecular Biology. 92(1):49-59, 2006.
- Iwamoto J et al. Effects of vitamin K2 on osteoporosis. Current Pharmaceutical Design. 10(21):2557-2576, 2004.
- Iwamoto J et al. Treatment with vitamin D3 and/or vitamin K2 for postmenopausal osteoporosis. The Keio Journal of Medicine. 2003 Sep;52(3):147-50. Review. · Neogi, T., et al. Low vitamin K status is associated with osteoarthritis in the hand and knee. Arthritis and Rheumatism. 54(4):1255-1261, 2006.
- Kameda T et al. Vitamin K2 inhibits osteoclastic bone resorption by inducing osteoclast apoptosis. Biochemical and Biophysical Research Communications. 220(3):515-519, 1996.
- Knapen M et al. Vitamin K2 supplementation improves hip bone geometry and bone strength indices in postmenopausal women. Osteoporosis International. 18(7):963-72, 2007.
- Kristal-Boneh E et al. Association of calcitriol and blood pressure in normotensive men. Hypertension. 30(5):1289-1294, 1997.
- Li Y et al. 1,25-Dihydroxyvitamin D(3) is a negative endocrine regulator of the renin-angiotensin system. Journal of Clinical Investigation. 110(2):229-238, 2002.
- Li Y et al. Vitamin D regulation of the renin-angiotensin system. Journal of Cell Biochemistry. 88(2):327-331, 2003.
- Li Y et al. Vitamin D: a negative endocrine regulator of the renin-angiotensin system and blood pressure. Journal of Steroid Biochemistry and Molecular Biology. 89-90(1-5):387-392, 2004.
- Nelsestuen G et al. Vitamin K-dependent proteins. Vitamins and Hormones. 58:355-389, 2000.
- Nimptsch K et al. Dietary intake of vitamin K and risk of prostate cancer in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition. American Journal of Clinical Nutrition. 87:985-992, 2008.
- Nouso K et al. Regression of hepatocellular carcinoma during vitamin K administration. World Journal of Gastroenterology. 11(42):6722-6724, 2005.
- Pfeifer M et al. Effects of a short-term vitamin D(3) and calcium supplementation on blood pressure and parathyroid hormone levels in elderly women. Journal of Clinical Endocrinology and Metabolism. 86(4):1633-1637, 2001.
- Price P. Role of vitamin K-dependent proteins in bone metabolism. Annual Review of Nutrition. 8:565-583, 1988.
- Schaafsma, A., et al. Vitamin D3 and vitamin K1 supplementation of Dutch postmenopausal women with normal and low bone mineral densities: effects on serum 25-hydroxyvitamin D and carboxylated osteocalcin. European Journal of Clinical Nutrition. 54:626-631, 2000.
- Schleithoff S et al. Vitamin D supplementation improves cytokine profiles in patients with congestive heart failure: a double-blind, randomized, placebo-controlled trial. American Journal of Clinical Nutrition. 83(4):754-759, 2006.
- Shearer M. Role of vitamin K and Gla proteins in the pathophysiology of osteoporosis and vascular calcification. Current Opinion in Clinical Nutrition and Metabolic Care. 3(6):433-438, 2000.
- Shiraki, M., et al. Vitamin K2 (menatetrenone) effectively prevents fractures and sustains lumbar bone mineral density in osteoporosis. Journal of Bone & Mineral Research. 15:515-522, 2000.
- Sigmund C. Regulation of renin expression and blood pressure by vitamin D(3). Journal of Clinical Investigation. 110(2):155-156, 2002.
- Taira H et al. Menatetrenone (vitamin K2) acts directly on circulating human osteoclast precursors. Calcified Tissue International. 73(1):78-85, 2003.
- Trivedi Det al. Effect of four monthly oral vitamin D3 (cholecalciferol) supplementation on fractures and mortality in men and women living in the community: randomised double blind controlled trial. British Medical Journal. 326(7387):469, 2003.
- Van den Berghe G et al. Bone turnover in prolonged critical illness: effect of vitamin D. Journal of Clinical Endocrinology and Metabolism. 88(10):4623-4632, 2003.
- Vasquez A et al. The clinical importance of vitamin D (cholecalciferol): a paradigm shift with implications for all healthcare providers. Alternative Therapies. 10(5):28-38, 2004.
- Weber P. Management of osteoporosis: is there a role for vitamin K? International Journal for Vitamin and Nutrition Research. 67(5):350-6, 1997.
- Yokoyama T et al. Combination of vitamin K2 plus imatinib mesylate enhances induction of apoptosis in small cell lung cancer cell lines. International Journal of Oncoloy. 26(1):33-40, 2005.
- Yoshida T et al. Apoptosis induction of vitamin K2 in lung carcinoma cell lines: the possibility of vitamin K2 therapy for lung cancer. International Journal of Oncology. 23(3):627-632, 2003.
- Zitterman A et al. Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? Journal of the American College of Cardiology. 41(1):105-112, 2003.
Product Label Details
This product is not registered under the Pharmacy and Poisons Ordinance or the Chinese Medicine Ordinance. Any claim made for it has not been subject to evaluation for such registration. This product is not intended to diagnose, treat or prevent any disease.

Reviews
Customer Rating
4.6 out of 5 star rating.
(12 reviews)
would recommend this product.
- Newest
- Highest Rating
- Lowest Rating
- Oldest
- Most Helpful
This is a great product, It helps me every day with more Energy and keeps me going!!!
Response from Customer Service on 6/3/2024
Dear Valued Customer,
Thank you for sharing your positive feedback with us! We're delighted to hear that you're enjoying the Isotonix® Vitamin D with K2 and experiencing the great benefits. Your feedback means a lot to us and it's always great to receive such kind words. If you have any questions or need further assistance, feel free to reach out to us anytime.
Thank you again,
The Product Information Team
Frist time using this and I just love it.
by SharonS
on 16/2/2023
Love this product and i can see the different right away, and it taste good.
Response from Customer Service on 17/2/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Vitamin D with K2! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
Shoppers found this review helpful
For those who don't like to go under the sun.
by EShop
Shop Consultant
on 16/6/2022
I love this D3 with K2 suppliment very much, as i hate to go under the sun and always stay in door, so i started this vit D for awhile.
When i went for a routine body check-up, my doctoc said that my D vit showed better then him. :)
Love the taste too.
Response from Customer Service on 16/6/2022
Dear Valued Customer,
Thank you for taking the time to leave your thoughts on the Isotonix® Vitamin D with K2. We are happy to hear you are pleased with the product.
Thank you again! Market Singapore Product Team
Must Get!
by BrianV
Shop Consultant
on 10/5/2022
One of my favorite products, tastes great, doesn't cake up. must try!
Response from Customer Service on 11/5/2022
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix® Vitamin D with K2! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
Shoppers found this review helpful
食用時間
by Anonymous
on 5/5/2022
這罐一定要空腹喝嗎?能否餐後?(查到維生素D任何時間服用都可以,餐後喝效果最好)
Response from Customer Service on 16/5/2022
感謝您聯絡美安公司。愛尚它®維生素D3 (含維生素K2)粉末建議用餐時飲用。提供您參考,謝謝您。
Shoppers found this review helpful
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