Benefits
- Supports a healthy complexion
- Helps support healthy skin collagen, elasticity and moisture
- Helps promote oxygen and nutrient supply to skin cells
- Provides antioxidant defense for the skin
- Supports normal cell growth
- Promotes healthy blood flow to skin cells
- Supports overall health

Product Classifications
Gluten-Free - The finished product contains no detectable gluten*
No Detectable GMO - The finished product contains no detectable genetically modified organisms
Vegetarian - This product is vegetarian
Isotonic-Capable Supplements - Easy-to-take isotonic supplements / health food that allow for better nutrient absorption by the body
Quality Standards - GMP Operations and Standardized Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Potency, Purity and Identity
*USA FDA classifies gluten-free as a finished product containing less than 20PPM gluten
Details
Isotonix OPC-3 Beauty Blend Powder Drink is formulated to support healthy skin collagen, elasticity and moisture. It provides vitamins and minerals that support a healthy complexion and it provides the skin and body with antioxidants. This product helps maintain skin health at the cellular level, nourishing and rejuvenating skin cells with some of the finest antioxidants available today including grape seed extract, red wine extract, bilberry extract, citrus bioflavonoid complex and Pycnogenol®†. These free-radical scavengers not only work to keep the skin healthy, but also provide free-radical-scavenging benefits. These antioxidants are coupled with specific vitamins and minerals that support cell health and growth.
Two of the most important factors when selecting a nutritional supplement are absorption and potency. The Isotonix delivery system, as found in Isotonix OPC-3 Beauty Blend Powder Drink, allows the body to absorb vitamins and minerals more rapidly. Isotonix food supplements, when mixed with water, actually have the same pH and osmotic pressure as the body's fluids such as tears, plasma and blood. In order for absorption of nutritional content to take place, all food must be converted into an isotonic state. However, our Isotonix OPC-3 Beauty Blend Powder Drink sets itself apart from other products on the market by providing you with the maximum absorption of nutrients, within the shortest amount of time. When an isotonic substance enters the body, it is rapidly absorbed into the bloodstream.
Oligomeric proanthocyanidins (OPCs) are bioflavonoids (complex organic plant compounds) found in fruits, vegetables and certain tree barks. Isotonix OPC-3 contains the only isotonic form of Pycnogenol in the world. Pycnogenol is a natural plant extract from the bark of the French maritime pine tree, and the most clinically-researched bioflavonoid.
Isotonic, which means “same pressure,” bears the same chemical resemblance of the body’s blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body’s common osmotic pressure, which is isotonic, allows a consistent maintenance of body tissues. In order for a substance to be absorbed and used in the body’s metabolism, it must be transported in an isotonic state.
Isotonix dietary supplements are delivered in an isotonic solution. This means that the body has less work to do to in obtaining maximum absorption. The isotonic state of the suspension allows nutrients to pass directly into the small intestine and be rapidly absorbed into the bloodstream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
*Pycnogenol® is registered trademark of Horphag Research, Ltd. Use of this product may be protected by one or more U.S patents and other international patents.

Learn More
Isotonix Delivery System

Ingredients
Grape Seed Extract
Grape seed extract is typically extracted from the seeds of red grapes (instead of white), which have a high content of compounds known as oligomeric proanthocyanidins (OPCs). Grape seed extract is extremely rich in polyphenols, compounds with high antioxidant activity.
Red Wine Extract
Red wine extract is a powerful antioxidant. This extract is found in grape vines, roots, seeds and stalks, with the highest concentration in the skins. The antioxidant properties of red wine extract contribute to healthy circulation which promotes oxygen and nutrient supply to skin cells.
Pine Bark Extract (Pycnogenol)
Pycnogenol is a natural plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. This unspoiled and natural forest environment is the unique source of pine bark. Pycnogenol is one of the most researched ingredients in the natural product marketplace. Published findings have demonstrated Pycnogenol’s wide array of beneficial effects on the body. Pine bark extract is an all-natural combination of procyanidins, bioflavonoids and organic acids.
Pynogenol acts as an antioxidant and may help to support healthy skin collagen, elasticity and moisture.
Bilberry Extract
Bilberry extract is derived from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins, which are antioxidants. Bilberry extract supports venous circulation which promotes oxygen and nutrient supply to all cells, especially those of the skin.
Citrus Bioflavonoid Complex
Bioflavonoids are antioxidants found in certain plants that act as light filters, which protect delicate DNA chains and other important macromolecules by absorbing ultraviolet radiation. They have been found to help maintain healthy circulation by strengthening blood vessels.
Hyaluronic Acid (Sodium Hyaluronate)
Hyaluronic acid or hyaluronate is a glycosaminoglycan distributed widely throughout connective, epithelial and neural tissues. It is one of the main constituents of the extracellular matrix and promotes healthy cell proliferation and migration. Plentiful in extracellular matrices, hyaluronic acid supports healthy tissue hydrodynamics, movement and production of cells, and promotes a number of cell surface receptor interactions.
Vitamin C (Ascorbic Acid)
Most vitamin C in the average diet is derived from fruits and vegetables. Peppers (sweet, green, red and hot) are especially rich in vitamin C. Other good sources include citrus fruits and juices, brussels sprouts, cauliflower, cabbage, kale, collards, mustard greens, broccoli, spinach, guava, kiwi fruit, currants and strawberries. Nuts and grains contain very little vitamin C, and it is important to note that cooking destroys vitamin C activity.
Vitamin C supports overall health and acts as an antioxidant. In fact, ascorbic acid may be the most well-known water-soluble antioxidant in the body. Vitamin C promotes the normal synthesis of collagen.
Vitamin D3 (Cholecalciferol)
Regular sunlight exposure is the main way that most humans obtain vitamin D. Food sources of vitamin D include vitamin D-fortified milk, cod liver oil, fatty fish (such as salmon) and small amounts are found in egg yolks and liver. It supports the normal growth of skin cells and a healthy complexion.
Vitamin E
The most valuable sources of dietary vitamin E include vegetable oils, margarine, nuts, seeds, avocados and wheat germ. Safflower oil contains large amounts of vitamin E, and smaller amounts are found in corn oil and soybean oil. Vitamin E is actually a family of related compounds called tocopherols and tocotrienols.
Through its antioxidant activity, vitamin E can help to protect cell membranes from free radical damage.
Biotin
Biotin is a part of the B-vitamin family. The B-vitamins are important co-factors, which promote the normal metabolism of fats, carbohydrates and protein. Natural food sources of biotin include egg yolk, peanuts, beef liver, milk, cereals, almonds and Brewer's yeast. Biotin operates as an important part of several enzymes. In the intestines, bacteria make a negligible amount of biotin that may be assimilated and used by the body. Biotin supports hair and nail health.
Calcium
Calcium is found in milk, cheese, yogurt, corn tortillas, napa (Chinese cabbage), kale and broccoli. Calcium is an essential mineral with a wide range of biological roles. The skeleton has an obvious structural requisite for calcium. The skeleton also acts as a storehouse for calcium. Apart from being a major constituent of bones and teeth, calcium supports overall health.
Calcium is essential for healthy bones and teeth. A sufficient daily calcium intake is necessary for maintaining bone density.
Magnesium
Foods rich in magnesium include unpolished grains, nuts and green vegetables. Green leafy vegetables are powerful sources of magnesium because of their chlorophyll content. Meats, starches and milk are less rich sources of magnesium. Refined and processed foods are generally quite low in magnesium.
Magnesium is a component of the mineralized part of bone. It helps maintain normal levels of potassium, phosphorus, calcium, adrenaline and insulin. It also promotes the mobilization of calcium, transporting it inside the cell for further utilization. Magnesium promotes strong bones and teeth and proper muscle development. It helps the body to maintain good blood circulation.
FAQ
What is Isotonix OPC-3 Beauty Blend Powder Drink? What exactly does it do?
Isotonix OPC-3 Beauty Blend Powder Drink is a revolutionary product that helps to improve and maintain the appearance of healthy, beautiful skin from the inside out. It uses the most powerful free-radical-scavenging antioxidants known to date. The purest and best-researched OPCs chosen for Isotonix OPC-3 Beauty Blend are derived from grapes, bilberries, Pycnogenol (pine bark) and citrus-fruit. These have the highest total polyphenol content. In addition to being powerful antioxidants, these OPCs also promote skin health. These powerful bioflavonoids are considered many times more powerful than vitamins C and E as free radical scavengers. They do, however, work well with both vitamin C and E.
Antioxidants found in Isotonix OPC-3 Beauty Blend Powder Drink scavenge free radicals within cells and promote optimal cellular functioning. The OPCs support your skin’s natural ability to regenerate new epidermal cells, paving the way for true splendor in the way of skin beautification. Isotonix OPC-3 Beauty Blend Powder Drink helps to replenish the skin’s vitamin and minerals which promote the growth and division of skin cells. It promotes a strong vascular network in the skin, thus supporting the elasticity of the skin. It also supports collagen production.
This combination of powerful OPCs is unique to Isotonix OPC-3 Beauty Blend Powder Drink as is the Isotonix delivery system, which enables rapid and highly efficient absorption of OPCs, vitamins and minerals.
Who should take Isotonix OPC-3 Beauty Blend Powder Drink?
Who wouldn’t want to be noticed for healthy-looking skin, especially when it’s cultivated at the cellular level where it really counts? All of us are constantly in contact with an environment that can be quite stressful upon the delicate nature of our skin. Everyone should take precautions against the effects of stress, aging and the environment when it comes to maintaining skin health. This product should be taken by anyone over the age of 18 who wants to look, feel and perform at their best, enabling them to reveal their beauty from the inside out.
Can men take Isotonix OPC-3 Beauty Blend Powder Drink?
Yes, this product is for anyone over the age of 18 who wants to have healthy, youthful-looking skin.
What is Pycnogenol?
Pycnogenol is the registered trademark of Horphag Research (UK) Ltd. for a standardized extract of bark of the French maritime pine tree. Pycnogenol is renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals. The flavonoids in Pycnogenol are powerful as antioxidants.
When can I expect results?
Within minutes after consumption of Isotonix OPC-3 Beauty Blend Powder Drink, the proanthocyanidins are delivered to the bloodstream where they immediately take action, supporting healthy blood flow. OPC-3 Beauty Blend Powder Drink supports healthy blood perfusion all over the body, which helps promote a healthy oxygen and nutrient supply as well as healthy waste removal. OPCs support collagen production in the skin, which increases smoothness and elasticity. It requires patience until skin cells have renewed significant amounts of collagen to show visible effects. Take Isotonix OPC-3 Beauty Blend Powder Drink to keep skin cells at their peak vitality. On a short-term basis, many people notice a fresher-looking skin complexion.
Can Isotonix OPC-3 Beauty Blend Powder Drink be mixed and consumed with other Isotonix products?
Yes. Isotonix OPC-3 Beauty Blend Powder Drink can be mixed and consumed with other Isotonix products that are taken on an empty stomach.
Can Isotonix OPC-3 Beauty Blend Powder Drink and Isotonix OPC-3 Powder Drink be mixed and consumed together?
Yes. Isotonix OPC-3 Beauty Blend Powder Drink and Isotonix OPC-3 Powder Drink can work well when consumed together.
Is Isotonix OPC-3 Beauty Blend Powder Drink safe?
Isotonix OPC-3 Beauty Blend Powder Drink is safe and free of harmful agents. The product is made in the United States in FDA-inspected facilities using Good Manufacturing Practices. Customers can have confidence in the quality and safety of this product.
Science
- Ames, BN, et al. Oxidants, antioxidants, and thedegenerative diseases of aging. Proc Natl Acad Sci USA 90:7915-7922, 1993.
- Bagchi, D, et al. Cellular protection withproanthocyanidins derived from grape seed. Ann NY Acad Sci 957:260-70, 2002.
- Bagchi, D, et al. Free radicals and grape seedproanthocyanidin extract: importance in human health and disease prevention.Toxicology 148: 187-97, 2000.
- Bagchi, D, et al. Oxygen free radical scavenging abilitiesof vitamins C and E, and a grape seed proanthocyanidin extract in vitro. ResCommun Mol Pathol Pharmacol 95:179-89, 1997.
- Bayeta, E., et al. Pycnogenol inhibits generation ofinflammatory mediators in macrophages. Nutrition Research 20: 249-259, 2000.
- Blazsó, G., et al. Anti-inflammatory and superoxideradical scavenging activities of a procyanidins containing extract from thebark of Pinus pinaster Sol. and its fractions. Pharm Pharmacol Lett 3: 217-20,1994.
- Cao G, Alessio H, Cultler R. Oxygen-radical absorbancecapacity assay for antioxidants. Fre Rad Biol & Med 14:301-11, 1993.
- Cho, K., et al. Effect of bioflavonoids extracted from thebark of Pinus maritima on proinflammatory cytokine interlukin-1 production inlipopolysaccharide-stimulated RAW 264. 7. Toxicology and Applied Pharmacology168: 64-71, 2000.
- Cho, K., et al. Inhibition mechanisms of bioflavonoidsextracted from the bark of Pinus maritima on the expression of proinflammatorycytokines. Annals of the NY Academy of Sciences 928: 141-156, 2001.
- Devaraj, S., et al. Supplementation with a pine barkextract rich in polyphenols increases plasma antioxidant capacity and altersthe plasma lipoprotein profile. Lipids 37:931-4, 2002.
- Drew B, Leeuwenburgh C. Aging and the role of reactivenitrogen species. Ann NY Acad Sci 959:66-81, 2002.
- Fine, AM, Oligomeric proanthocyanidin complexes: history,structure, and phytopharmaceutical applications. Altern Med Rev 5:144-51, 2000.
- Fitzpatrick, D., et al. Endothelium-dependent vasculareffects of Pycnogenol. Journal of Cardiovascular Pharmacology 32: 509-515,1998.
- Frankel, E., et al. Inhibition of oxidation of humanlow-density lipoprotein by phenolic substances in red wine. Lancet 341: 454-7,1993.
- Freedman, J., et al. Select flavonoids and whole juicefrom purple grapes inhibit platelet function and enhance nitric oxide release.Circulation 103:2792-8, 2001.
- Frémont, L. Biological effects of resveratrol. LifeSciences 66: 663-673, 2000.
- Gibson, L, et al. Effectiveness of cranberry juice inpreventing urinary tract infections in long-term care facility patients. JNaturopathic Med 2:45-47, 1991.
- Graham DY, Smith JL, Bouvet, AA. What happens to tabletsin the stomach. J Pharm Sci 79:420-24, 1990.
- Gulati, O. Pycnogenol® in venous disorders: a review.European Bulletin of Drug Research 7: 1-13, 1999.
- Havsteen B. Flavonoids, a class of natural products ofhigh pharmacological potency. Biochem Pharm 32:1141-48, 1983.
- Hosseini, S., et al. Pycnogenol® in the management ofasthma. Journal of Medicinal Food 4: 201-209, 2001.
- Joseph JA, Shukitt-Hale B, Denisova NA, Bielinksi D,Martin A, McEwen JJ, Bickford PC. Reversals of age-related declines in neuronalsignal transduction, cognitive, and motor behavioral deficits with blueberry,spinach, or strawberry dietary supplementation. J Neuroscience 19: 8114-21,1999.
- Kay CD, Holub BJ. The effect of wild blueberry (Vacciniumangustifolium) on post-prandial serum antioxidant status in human subjects. BrJ Nutr 88: 389-98, 2002.
- Kehrer JP. Free radicals as mediators of tissue injury anddisease. Crit Rev Toxicol 23:21-48, 1993.
- Koch R. Comparative study of Venostatin and Pycnogenol inchronic venous insufficiency. Phytother Res 16:S1-5, 2002.
- Kohama, T., et al. Analgesic efficacy of French maritimepine bark extract in dysmenorrhea. Journal of Reproductive Medicine 49: 828-32,2004.
- Kohama, T., et al. The treatment of gynecologicaldisorders with Pycnogenol®. European Bulletin of Drug Research 7: 30-32, 1999.
- Koparker AD, Augsburger LL, Shangraw RF. Intrinsicdissolution rates of tablet fillers and binders and their influence on thedissolution of drugs from tablet formulations. Pharm Res 7:80-85, 1990.
- Liu, X., et al. Antidiabetic effect of Pycnogenol Frenchmaritime pine bark extract in patients with diabetes type II. Life Sci75:2505-13, 2004.
- Liu, X., et al. French maritime pine bark extractpycnogenol dose-dependently lowers glucose in type 2 diabetic patients.Diabetes Care 27: 839, 2004.
- Manna, S., et al. Resveratrol suppresses TNF-Inducedactivation of nuclear transcription factors NF-kB, activator protein-1, andapoptosis: potential role of reactive oxygen intermediates and lipidperoxidation. The Journal of Immunology 164: 6509-19, 2000.
- Mazza G,Kay CD, Cottrell T, Holub BJ. Absorption of anthocyanins from blueberries andserum antioxidant status in human subjects. J Agric Food Chem 50:7731-37, 2002.
- Miyagi,Y., et al. Inhibition of human low-density lipoprotein oxidation by flavonoidsin red wine and grape juice. Am J Cardiol 0:1627-31, 1997.
- Monograph.Vaccinium myrtillus (bilberry). Altern Med Rev 6:500-4, 2001.
- MuriasM., et al. Resveratrol analogues as selective cyclooxygenase-2 inhibitors:synthesis and structure-activity relationship. Bioorg Med Chem 12: 5571-8,2004.
- NesaretnamK, et al. Effect of tocotrienols on the growth of a human breast cancer cellline in culture. Lipids 30:1139-43, 1995.
- NuttallSL, Kendall MJ, Bombardelli E, Morazzoni P. An evaluation of the antioxidantactivity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther23: 385-89, 1998.
- Ofek I,Goldhar J, Zafriri D, Lis H, Sharon N. Anti-Escherichia coli adhesion activityof cranberry and blueberry juices. New England J Med 324:1599, 1991.
- Packer,L., et al. Antioxidant activity and biologic properties of a procyanidin-richextract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med27:704-24, 1999. Review.
- Qureshi,A, et al. Response of hypercholesterolemic subjects to administration oftocotrienols. Lipids 30:1171-77, 1995.
- RimbachG, Virgili F, Park YC, Packer L. Effect of procyanidins from Pinus maritime onglutathione levels in endothelial cells challenged by 3-morpholinosydnonimineor activated macrophages. Redox Rep 4:171-77, 1999.
- Rohdewald,P. A review of the French maritime pine bark extract (Pycnogenol®), a herbalmedication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther40:158-68, 2002. Review.
- Rohdewald,P. Pycnogenol®. In “Flavonoids in Health and Disease”. Ed. Catherine Rice-Evansand Lester Packer. New York: Marcel Dekker, Inc., 1998. 405-19.
- Roseff,S., et al. Improvement in sperm quality and function with French maritime pinetree bark extract. Journal Reproductive Medicine 47: 821-4, 2002.
- Roseff,S., et al. Improvement of sperm quality by Pycnogenol®. European Bulletin ofDrug Research 7: 33-6, 1999.
- Saito,M., et al. Antiulcer activity of grape seed extract and procyanidins. J AgricFood Chem 46: 1460-4, 1998.
- Schönlau,F., et al. Pycnogenol® for diabetic retinopathy. International Ophthalmology24: 161-171, 2002.
- Schönlau,F., et al. The cosmeceutical Pycnogenol®. J Appl Cosmetology 20: 241-6, 2002.
- Segger,D. and Schönlau, F. Supplementation with Evelle® improves skin smoothness andelasticity in a double blind, placebo-controlled study with 62 women. Journalof Dermatological Treatment 15:222-26, 2004.
- Sharma,S., et al. Pycnogenol® inhibits the release of histamine from mast cells.Phytotherapy Research 17: 66-69, 2003.
- Shi, J.,et al. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food6:291-9, 2003. Review.
- SobotaAE. Inhibition of bacterial adherence by cranberry juice: powerfulial use forthe treatment of urinary tract infactions. J Urology 131:1013-1016, 1984.
- SolowayMS, Smith RA. J Am Med Assoc 260:1465, 1988.
- Spadea,L., et al. Treatment of vascular retinopathies with Pycnogenol®. PhytotherapyResearch 15: 219-23, 2001.
- Stein,J., et al. Purple grape juice improves endothelial function and reduces thesusceptibility of LDL cholesterol to oxidation in patients with coronary arterydisease. Circulation 100:1050-5, 1999.
- Takada,Y., et al. Nonsteroidal anti-inflammatory agents differ in their ability tosuppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 andcyclin D1, and abrogation of tumor cell proliferation. Oncogene 23: 9247-58,2004.
- Tomco, A,et al. Antioxidant effects of tocotrienol in patients with hyperlipidemia andcarotid stenosis. Lipids 30: 1179-83, 1995.
- Ueda, T.,et al. Preventative effect of natural and synthetic antioxidants on lipidperoxidation in the mammalian eye. Ophthalmic Res 28: 184-92, 1996.
- Wallerath,T., et al. Resveratrol, a polyphenolic phytoalexin present in red wine,enhances expression and activity of endothelial nitric oxide synthase.Circulation 106:1652-8, 2002.
- Watson,R. Pycnogenol® and cardiovascular health. Evidence-Based Integrative Medicine1: 27-32, 2003.
- Wei, Z.,et al. Pycnogenol enhances endothelial cell antioxidant defense. Redox Report3: 219-24, 1997.
- Yamakoshi,J., et al. Proanthocyanidin-rich extract from grape seeds attenuates thedevelopment of aortic atherosclerosis in cholesterol-fed rabbits.Atherosclerosis 142:139-149, 1999.
- Zheng W,Wang SY. Oxygen radical absorbing capacity of phenolics in blueberries,cranberries, chokeberries, and lingonberries. J Agric Food Chem 51:502-9, 2003.
- Halpern,MJ, et al. Red wine polyphenols and inhibition of platelet aggregation:possible mechanisms, and potential use in health promotion and diseaseprevention. J Int Med Res 26:171-80, 1998.
Reviews
Customer Rating
4.9 out of 5 star rating.
(38 reviews)
would recommend this product.
- Newest
- Highest Rating
- Lowest Rating
- Oldest
- Most Helpful
Ketika kekurangan vitamin, ini adalah produk yang tepat karena telah menggambungkan beberapa antioksidan dan vitamin.
Overall very recommended!
LOVE LOVE LOVE!!!
by JUDIM
Shop Consultant
on 4/9/2024
This product is the foundation that I build my healthy lifestyle on!!
Response from Customer Service on 5/9/2024
Thank you for your enthusiastic review! We're thrilled to hear that our product plays such a crucial role in your healthy lifestyle. Your passion and satisfaction mean a lot to us!
素食可食用吗?
by Anonymous
on 21/6/2022
请问素食者可以吃吗?
Response from Customer Service on 22/6/2022
Dear Valued Customer,
Isotonix™ Globeau OPC-3™ Plus Powder contains Vitamin D derived from wool, thus it is not suitable for vegetarians.
Thank you.
UnFranchise Services Department
美颜OPC
by Anonymous
on 1/6/2022
味道很好,颜色很漂亮
原本有点暗淡的肤色有被提亮的感觉
Response from Customer Service on 4/6/2022
Dear Valued Customer,
Thank you for taking the time to leave your thoughts on the Isotonix™ Globeau OPC-3™ Plus Powder. We are happy to hear you are pleased with the product.
Thank you.
UnFranchise Services Department
正
by Miranda Man YeeW
Shop Consultant
on 2/1/2022
飲咗之後皮膚多咗光澤,值得推介
Response from Customer Service on 3/1/2022
致 親愛的顧客,
感謝您抽出寶貴時間對 Isotonix®美肌OPC-3®沖飲 發表意見。我們很高興您對產品感到滿意。
再次感謝閣下對美安的支持!
Share this page!
Copy this link and paste to your favorite social, blog or website.
Link copied! Please paste and share on your favorite platforms.
There was an error copying to your clipboard. Please try again later.